Recherche scientifique et médicale

Notre service est très actif dans la recherche aussi bien translationnelle que clinique. Notre unité de recherche fait partie de l’unité INSERM UMR 1152 (physiopathologie et épidémiologie des maladies respiratoires)

Les principales thématiques sont :

L’atteinte pulmonaire au cours de la polyarthrite rhumatoïde

o MUC5B Promoter Variant and Rheumatoid Arthritis with Interstitial Lung Disease
o A Risk Score to Detect Subclinical Rheumatoid Arthritis-Associated Interstitial Lung Disease
o MUC5B promoter variant rs35705950 and rheumatoid arthritis associated interstitial lung disease survival and progression
o Methotrexate and rheumatoid arthritis associated interstitial lung disease
o Shared genetic predisposition in rheumatoid arthritis-interstitial lung disease and familial pulmonary fibrosis
o RPA3-UMAD1 rs12702634 and rheumatoid arthritis-associated interstitial lung disease in European ancestry
o Value of lung ultrasonography for screening interstitial lung disease in patients with rheumatoid arthritis
o Effectiveness and tolerability of antifibrotics in rheumatoid arthritis-associated interstitial lung disease

L’imagerie au cours des rhumatismes inflammatoires et microcristallin

o Fluorine-18 fluorodeoxyglucose positron emission tomography/computed tomography in polymyalgia rheumatica: an observational study
o Salivary gland ultrasonography in patients with connective tissue diseases: a multi-centre observational study
o Ultrasound evaluation in follow-up of urate-lowering therapy in gout: the USEFUL study
o UltraSound evaluation in follow-up of urate-lowering therapy in gout phase 2 (USEFUL-2): Duration of flare prophylaxis
o Enthesopathy in rheumatoid arthritis and spondyloarthritis: An ultrasound study
o Ankle retinacula abnormalities as features of psoriatic arthritis: An ultrasound study

Autres

o Screening for spondyloarthritis in patients with inflammatory bowel diseases
o Increased risk of mortality in lung transplant patients with fragility fractures
o Osteoporotic vertebral fracture during non-small cell lung cancer – the BONE study
o A disseminated gonococcal infection with spinal locations
o Cardiac myxoma mimicking a spondyloarthritis flare.

Par ailleurs, nous participons activement à de nombreux protocoles de recherche clinique et registres, dans le domaine des rhumatismes inflammatoires, microcristallins et connectivite.

Bureau de Recherche Clinique :

Hagit ZYLBERMAN-YONA
Tel 01 40 25 70 27